- Could schizophrenia and bipolar disorder within a family be caused by the same mutation(s) but expressed differently based on differences in environment and the family member's gender? Bipolar being the less severe form and schizophrenia being the more severe form? Females tend to have bipolar disorder and males schizophrenia?
- Could schizophrenia and bipolar result from the cumulative effect of several mutations in various genes and not any one significant mutation? Or one significant mutation plus others? In some cases, one severe mutation?
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