Tuesday, October 17, 2017

Resistance SNPs

Some variants offer some protection against certain disease or at least slow down the progression of disease.  Or so we think...

rs1799864 = A (minor allele A is associated with slower HIV progression).
rs1799990 = G (If heterozygous some resistance to prion diseases like Creutzfeldt Jacobs).
rs601338 = A (If homozygous for minor allele A there is some resistance to norovirus but may have increased risk for celiac and IBD).
rs8177374 = T (With minor allele T less susceptible to malaria, tuberculosis, bacteremia and pneumococcal disease).  Good thing I have one T!  The minor allele is not the most common either with minor allele frequency (MAF) of 0.084. 
rs2853826 = G (Some resistance to developing Parkinson's disease.  The snp is on the mtDNA. Interesting).
rs4804803 = A (Some protection against tuberculosis).
rs1334512 = G (Decreased risk for developing severe malaria).

No comments:

Post a Comment

SI Joint Pain and Bursitis in both Hips

It looks like 23andme does not test for enough markers relating to psoriatic arthritis and ankylosing spondylitis.  I recently developed wha...